Understanding erectile dysfunction medication preference studies.

John P Mulhall

doi:10.1097/00042307-200411000-00013

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Understanding erectile dysfunction medication preference studies.

John P Mulhall

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Abstract

PURPOSE OF REVIEW: The existence of three phosphodiesterase 5 inhibitors has resulted in an increase in the marketing of the drugs. This has led to a shift in focus from scientifically rigorous endpoints such as efficacy and adverse event profiles to patient preference. RECENT FINDINGS: Although no consensus currently exists as to the correct methodology for preference studies, some basic guidelines should be adhered to, including: (1) the double-blinding of drug administration; (2) non-biased drug administration instructions; (3) an adequately conducted crossover study; (4) comparison of equivalent doses; (5) standardized preference assessment; (6) declaration of patient demographics; and (7) rigorous statistical analysis. These factors are discussed in the light of the three published preference studies. SUMMARY: In the final analysis, it is unclear to this author how preference studies impact upon clinician decision-making when confronted by a patient with erectile dysfunction.

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Clinical Trials as Topic Cross-Over Studies Data Interpretation, Statistical Erectile Dysfunction Humans Male Phosphodiesterase Inhibitors Practice Patterns, Physicians'Journal Article Review

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John P Mulhall. 2004. Understanding erectile dysfunction medication preference studies.. https://doi.org/10.1097/00042307-200411000-00013

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