HIV treatment models with time delay.

Mostafa Bachar; Anita Dorfmayr

doi:10.1016/j.crvi.2004.08.007

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HIV treatment models with time delay.

Mostafa Bachar·Anita Dorfmayr

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Abstract

The present paper shows possible effects of antiretroviral treatment on the dynamics of the spread of the disease of human immunodeficiency virus infection in a population of varying size. By introducing time delays, we model the latency period and the delayed onset of positive treatment effects in the patients. The Hopf bifurcation and stability behaviour of the delay differential-equation model are analysed and simulations for different scenarios depending on the size of the treatment-induced delay are presented, and the results are discussed in detail.

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Acquired Immunodeficiency Syndrome Anti-HIV Agents Drug Administration Schedule HIV Infections Humans Lymphocyte Count Mathematics Models, Biological Time Factors Journal Article Research Support, Non-U.S. Gov't Review

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Mostafa Bachar, Anita Dorfmayr. 2004. HIV treatment models with time delay.. https://doi.org/10.1016/j.crvi.2004.08.007

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