Interactive DNA sequence and structure design for DNA nanoapplications.

Mingjun Zhang; Chaman L Sabharwal; Weimin Tao; Tzyh-Jong Tarn; Ning Xi; Guangyong Li

doi:10.1109/tnb.2004.837918

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Interactive DNA sequence and structure design for DNA nanoapplications.

Mingjun Zhang·Chaman L Sabharwal·Weimin Tao·Tzyh-Jong Tarn·Ning Xi·Guangyong Li

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Abstract

DNA sequence and structure design is very important for DNA nanoapplications. A computer-aided design tool is needed for exploring DNA sequence and structure of interests before experimental synthesis, which is a time- and labor-consuming process. In this paper, an interactive DNA sequence and structure design software tool called DNA shop is proposed and implemented. The visualization tool can generate DNA structures by specifying, selecting, and moving DNA sequences around and display corresponding structures. Using the tool, DNA sequence and structure can be visually inspected in three-dimensional space before experimental studies.

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Algorithms Base Sequence Computer Graphics Computer Simulation Computer-Aided Design DNA DNA Probes Imaging, Three-Dimensional Models, Chemical Models, Molecular Molecular Sequence Data Nanotechnology Nucleic Acid Conformation Sequence Analysis, DNA Software User-Computer Interface Journal Article

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Mingjun Zhang, Chaman L Sabharwal, Weimin Tao, Tzyh-Jong Tarn, Ning Xi, Guangyong Li. 2004. Interactive DNA sequence and structure design for DNA nanoapplications.. https://doi.org/10.1109/tnb.2004.837918

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