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Bacterial conjugation: a potential tool for genomic engineering.

Matxalen Llosa·Fernando de la Cruz
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Abstract

Bacterial conjugation is a mechanism for horizontal DNA transfer with potential for universal DNA delivery. The conjugal machinery can be separated into three functional modules: the relaxosome, the coupling protein, and a type IV protein secretion system. Module interchangeability among different conjugative systems opens up the possibility of "a la carte" engineering of DNA delivery into virtually any cell type.

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BacteriaConjugation, GeneticDNA, BacterialGene Transfer, HorizontalGenetic EngineeringJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Matxalen Llosa, Fernando de la Cruz. Bacterial conjugation: a potential tool for genomic engineering.. https://doi.org/10.1016/j.resmic.2004.07.008

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