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PubMed · 15640098

[Transposable element mariner].

Hui Zhang·Xiao-Ke Wang·Shi-Jun Ma
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Abstract

Mariner and mariner-like elements (MLEs) have been found in a wide range of organisms including human since its discovery in Drosophila mauritiana. MLEs belong to the mariner/Tc1 superfamily, one of the most diverse and widespread Class II transposable elements. MLEs have a conserved "D,D(34)D" motif in their transposases and they transpose by cut-and-paste mechanisms. Their extraordinarily wide host range and horizontal transmission in distantly related species indicate that they do not need additional host-specific factors for transposition. The evidence that MLEs could transform a wide variety of organisms especially the vertebrates supported the host-independent mechanism and suggested the availability as a kind of potential transforming vector.

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AnimalsDNA Transposable ElementsDNA-Binding ProteinsDrosophilaEvolution, MolecularGenetic VectorsHumansTransformation, GeneticTransposasesEnglish AbstractJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Hui Zhang, Xiao-Ke Wang, Shi-Jun Ma. 2004. [Transposable element mariner].. https://pubmed.ncbi.nlm.nih.gov/15640098/

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