Using ontologies to describe mouse phenotypes.

Georgios V Gkoutos; Eain C J Green; Ann-Marie Mallon; John M Hancock; Duncan Davidson

doi:10.1186/gb-2004-6-1-r8

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Using ontologies to describe mouse phenotypes.

Georgios V Gkoutos·Eain C J Green·Ann-Marie Mallon·John M Hancock·Duncan Davidson

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Abstract

The mouse is an important model of human genetic disease. Describing phenotypes of mutant mice in a standard, structured manner that will facilitate data mining is a major challenge for bioinformatics. Here we describe a novel, compositional approach to this problem which combines core ontologies from a variety of sources. This produces a framework with greater flexibility, power and economy than previous approaches. We discuss some of the issues this approach raises.

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Animals Computational Biology Disease Models, Animal Genotype Humans Medical Informatics Mice Phenotype Vocabulary, Controlled Journal Article Research Support, Non-U.S. Gov't

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Georgios V Gkoutos, Eain C J Green, Ann-Marie Mallon, John M Hancock, Duncan Davidson. 2004-12-20. Using ontologies to describe mouse phenotypes.. https://doi.org/10.1186/gb-2004-6-1-r8

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