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Kinases regulating Golgi apparatus structure and function.

Christian Preisinger·Francis A Barr
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Abstract

Protein kinases control Golgi function in both mitotic and interphase cells. In mitosis, phosphorylation of structural proteins by Cdk1 (cyclin-dependent kinase 1)-cyclin B, Polo-like and mitogen-activated protein kinases underlie changes in Golgi reorganization during cell division. While in interphase, signalling pathways that are associated with the Golgi control secretory function through a variety of mechanisms. Some of these, notably those involving protein kinase D and Ste20 family kinases, are also relevant for the establishment and maintenance of cell polarization and migration.

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AnimalsCell MovementCell PolarityGolgi ApparatusHumansInterphaseMitosisProtein KinasesSignal TransductionJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Christian Preisinger, Francis A Barr. 2005. Kinases regulating Golgi apparatus structure and function.. https://doi.org/10.1042/bss0720015

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