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PubMed · 15657479

Nanostructured systems for biological materials.

Esther H Lan·Bruce Dunn·Jeffrey I Zink
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Abstract

The sol-gel process is a chemical technique for immobilizing biomolecules in an inorganic, transparent matrix. The dopant biomolecules reside in an interconnected mesoporous network and become part of the nanostructured architecture of the entire material. In this chapter, we review the sol-gel immobilization approach and discuss how it leads to the stabilization of a number of proteins against aggressive chemical and thermal environments. We also review the sensor applications of this material that result from having analyte molecules diffuse through the matrix and reach the immobilized biomolecule.

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Biosensing TechniquesCircular DichroismCreatine KinaseEnzyme StabilityGlassHot TemperatureImmunoassayNanotechnologyTime FactorsJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.Review

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Esther H Lan, Bruce Dunn, Jeffrey I Zink. 2005. Nanostructured systems for biological materials.. https://doi.org/10.1385/1-59259-858-7%3A053

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