Is IS(ABA-1) customized for Acinetobacter?

Heidi Segal; Seike Garny; B Gay Elisha

doi:10.1016/j.femsle.2005.01.005

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PubMed · 15686845

Is IS(ABA-1) customized for Acinetobacter?

Heidi Segal·Seike Garny·B Gay Elisha

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Abstract

An insertion sequence (IS(ABA-1)) was identified in Acinetobacter spp., but not in Enterobacteriacea and Pseudomonas aeruginosa. Numerous copies of the IS were identified in Acinetobacter strains containing the element. In one of the Acinetobacter baumannii strains, IS(ABA-1) was identified adjacent to sulII and transcription of the resistance gene is presumed to be dependent on promoter sequences within the IS. Since the IS is adjacent to ampC and bla(OXA) in this A. baumannii strain, it may be that IS(ABA-1) plays an important role in the expression of antibiotic resistance genes in this genus.

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Acinetobacter Acinetobacter baumannii Anti-Bacterial Agents Base Sequence Cloning, Molecular DNA Transposable Elements Drug Resistance, Bacterial Enterobacteriaceae Humans Microbial Sensitivity Tests Molecular Sequence Data Pseudomonas aeruginosa Sequence Analysis, DNA Sulfonamides Journal Article Research Support, Non-U.S. Gov't

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Heidi Segal, Seike Garny, B Gay Elisha. 2005-02-15. Is IS(ABA-1) customized for Acinetobacter?. https://doi.org/10.1016/j.femsle.2005.01.005

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