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Chemosensitivity in pediatric dermatofibrosarcoma protuberans.

Antony Ng·Hiroshi Nishikawa·Anthony Lander·Richard Grundy
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Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare tumor of fibrohistiocytic spectrum and uncommonly presents in infancy and childhood. The standard treatment is wide-margin surgical excision, but this is difficult to achieve in large tumors and may result in unacceptable cosmetic, structural, and functional consequences. The authors describe a child with recurring DFSP who, after extensive surgery, responded to treatment with vinblastine and oral methotrexate. This is the first reported case in literature of a chemotherapeutic response in pediatric DFSP.

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Administration, OralAntineoplastic Combined Chemotherapy ProtocolsChildDermatofibrosarcomaFemaleHumansMethotrexateNeoplasm Recurrence, LocalSkin NeoplasmsVinblastineCase ReportsJournal Article

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Antony Ng, Hiroshi Nishikawa, Anthony Lander, Richard Grundy. 2005. Chemosensitivity in pediatric dermatofibrosarcoma protuberans.. https://doi.org/10.1097/01.mph.0000152861.05622.99

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