A new linker for anchoring/masking primary amines on solid support.

Antonietta Paladino; Claudia Mugnaini; Maurizio Botta; Federico Corelli

doi:10.1021/ol047710k

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PubMed · 15704895

A new linker for anchoring/masking primary amines on solid support.

Antonietta Paladino·Claudia Mugnaini·Maurizio Botta·Federico Corelli

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Abstract

A polymer-supported diketone was synthesized and used to fully protect/mask primary amines by the formation of a pyrrole ring. Various reactions can be performed on this system which then can be cleaved with full restoration of the amine functionality. The resin can also be recycled at least once without loss of purity of the final compound. [structure: see text]

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Amines Ketones Models, Molecular Pyrroles Journal Article Research Support, Non-U.S. Gov't

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Antonietta Paladino, Claudia Mugnaini, Maurizio Botta, Federico Corelli. 2005-02-17. A new linker for anchoring/masking primary amines on solid support.. https://doi.org/10.1021/ol047710k

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