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PubMed · 1570893

Segregation and linkage analysis.

R C Elston
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Abstract

Computer programs are available in the software package SAGE to perform a variety of segregation and linkage analyses used by human geneticists. These methods are designed specifically to uncover major gene segregation in pedigree data coming from non-inbred populations. With the aid of a closely linked polymorphic marker, they can detect a locus that contributes as little as 10% to the variation of a quantitative trait in a pedigree sample of several hundred individuals.

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R C Elston. 1992. Segregation and linkage analysis.. https://pubmed.ncbi.nlm.nih.gov/1570893/

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