Interpretive criteria for disk diffusion tests using 5-microgram cefdinir disks with rapidly growing clinical isolates.

R N Jones; M E Erwin; B B Gooding

doi:10.1128/jcm.30.4.1022-1023.1992

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Interpretive criteria for disk diffusion tests using 5-microgram cefdinir disks with rapidly growing clinical isolates.

R N Jones·M E Erwin·B B Gooding

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Abstract

Preliminary interpretive zone diameter criteria were calculated for the 5-micrograms cefdinir disk diffusion test by using two potential MIC breakpoints (less than or equal to 0.5 and less than or equal to 1 micrograms/ml). The absolute agreement between tests ranged from 85.9 to 92.4%, and the false-susceptibility errors were principally contributed by the Enterobacter spp. (2.2% error). One proposed criterion was greater than or equal to 20-mm zone diameter (less than or equal to 1 micrograms/ml) for susceptibility and less than or equal to 16-mm zone diameter (greater than 2 micrograms/ml) for resistance to cefdinir. Clinical laboratory users of the disk diffusion method should be cautioned about the possibility of very major interpretive errors among enterobacter isolates.

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Cefdinir Cephalosporins Diagnostic Errors Enterobacter Evaluation Studies as Topic Humans Microbial Sensitivity Tests Comparative Study Journal Article Research Support, Non-U.S. Gov't

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R N Jones, M E Erwin, B B Gooding. 1992. Interpretive criteria for disk diffusion tests using 5-microgram cefdinir disks with rapidly growing clinical isolates.. https://doi.org/10.1128/jcm.30.4.1022-1023.1992

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