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PubMed · 15732663

Antihypertensive pharmacogenetics.

J Braz Nogueira
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Abstract

Essential hypertension is a complex disease in which multiple genetic and environmental factors interact to produce the phenotype. The genetic contribution to blood pressure variations is estimated to range from 30% to 50%. In this review we describe some of the genes and genetic polymorphisms that have been most consistently related to blood pressure elevation and also the importance of pharmacogenetics and the emerging evidence of genetic influences on antihypertensive drug responses, with the potential for getting the right drug into the right patient based on the individual genetic profile.

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Antihypertensive AgentsHumansHypertensionPharmacogeneticsRenin-Angiotensin SystemJournal ArticleReview

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J Braz Nogueira. 2004. Antihypertensive pharmacogenetics.. https://pubmed.ncbi.nlm.nih.gov/15732663/

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