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PubMed · 15753201

Controlling inflammation: a fat chance?

Roderick J Flower·Mauro Perretti
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Abstract

The inflammatory response protects the body against infection and injury but can itself become deregulated with deleterious consequences to the host. It is now clear that several endogenous biochemical pathways activated during defense reactions can counterregulate inflammation. New experimental evidence adds resolvin E1 to this group of endogenous inhibitors and provides further rationale for the beneficial effects of dietary supplementation with fish oils. It also highlights an unexpected twist in the pharmacology of aspirin.

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AnimalsAnti-Inflammatory AgentsAspirinDietary FatsFatty Acids, UnsaturatedHumansInflammationReceptors, G-Protein-CoupledJournal ArticleReview

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Roderick J Flower, Mauro Perretti. 2005-03-07. Controlling inflammation: a fat chance?. https://doi.org/10.1084/jem.20050222

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