What have we learnt about microarray analyses of atherogenesis?

Tiina T Tuomisto; Seppo Ylä-Herttuala

doi:10.1097/01.mol.0000162325.85290.e5

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What have we learnt about microarray analyses of atherogenesis?

Tiina T Tuomisto·Seppo Ylä-Herttuala

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Abstract

PURPOSE OF REVIEW: This review covers recent developments in microarray studies in the field of atherogenesis research. RECENT FINDINGS: During the past year microarrays have been applied to the analysis of pathogenic mechanisms of several atherosclerosis risk factors, including ageing, hypertension, obesity, and cytomegalovirus infection. In addition, gene expression patterns during the development of in-stent restenosis have been examined. Several studies have also explored the pleiotropic effects of statin therapy. As a technical improvement, the combination of laser microdissection with microarrays in human samples has been reported. SUMMARY: Microarray analyses have given important new information about atherogenesis. It is anticipated that microarray studies will significantly contribute to further discoveries in the field.

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Aging Animals Arteriosclerosis Cells, Cultured Cytomegalovirus Infections Gene Expression Profiling Humans Hypertension Obesity Oligonucleotide Array Sequence Analysis Rats Risk Factors Journal Article Research Support, Non-U.S. Gov't Review

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Tiina T Tuomisto, Seppo Ylä-Herttuala. 2005. What have we learnt about microarray analyses of atherogenesis?. https://doi.org/10.1097/01.mol.0000162325.85290.e5

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