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PubMed · 15775606

[Pathogenesis of adynamic bone disease].

H Ogata·T Ito·E Kinugasa
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Abstract

Both relative hypoparathyroidism and low turnover bone play crucial roles in the pathogenesis of adynamic bone disease (ABD), which is the most common form renal osteodystrophy (ROD). In addition to individual factors, including diabetes, elder age, and/or uremic toxins, dialysis therapy and treatment for ROD, administration of calcium-containing phosphorus binder or active vitamin D (VD) metabolite, are associated with the pathological processes. Recently it has been suggested a potential association ABD and VD receptor polymorphism, or malnutrition state.

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H Ogata, T Ito, E Kinugasa. 2001. [Pathogenesis of adynamic bone disease].. https://pubmed.ncbi.nlm.nih.gov/15775606/

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