PubMed · 15783705
Colloidal interactions and self-assembly using DNA hybridization.
Abstract
The specific binding of complementary DNA strands has been suggested as an ideal method for directing the controlled self-assembly of microscopic objects. We report the first direct measurements of such DNA-induced interactions between colloidal microspheres, as well as the first colloidal crystals assembled using them. The interactions measured with our optical tweezer method can be modeled in detail by well-known statistical physics and chemistry, boding well for their application to directed self-assembly. The microspheres' binding dynamics, however, have a surprising power-law scaling that can significantly slow annealing and crystallization.
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Paul L Biancaniello, Anthony J Kim, John C Crocker. 2005-02-10. Colloidal interactions and self-assembly using DNA hybridization.. https://doi.org/10.1103/physrevlett.94.058302
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