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PubMed · 1580847

Sample size calculations for ophthalmologic studies.

W J Gauderman·W E Barlow
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Abstract

Sample size calculations are shown for some common ophthalmologic study designs in which two treatments are to be compared. Included are the following three designs: 1, only one eye per subject; 2, both eyes, with each eye assigned to a different treatment; and 3, both eyes undergoing a common treatment. Continuous and binary outcomes are considered. The correlation between eyes is accounted for in the computations using a simple correction factor. For design 3, the formulas allow for a mixture of single-eye and double-eye eligible subjects. A computer program that performs the calculations is available.

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HumansOphthalmologyResearch DesignSoftwareStatistics as TopicVision, BinocularVision, MonocularJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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BibTeXRIS

W J Gauderman, W E Barlow. 1992. Sample size calculations for ophthalmologic studies.. https://doi.org/10.1001/archopht.1992.01080170112036

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