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PubMed · 15812130

Sodium stibogluconate and polymorphic ventricular tachycardia.

Arun K Baranwal·Ravi N Mandal·Rupa Singh·Sunit C Singhi
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Abstract

Numerous antimicrobials including pentavalent antimonials are implicated in causing prolong QT-interval and ventricular tachycardia. Torsades de pointes is rarely documented with use of sodium stibogluconate. Here is described a 12-yr-old girl with visceral leishmaniasis, who developed syncopal attacks, prolong QT-interval, polymorphic ventricular tachycardia and torsades de pointes after completing a course of Stibogluconate (20 mg/kg/day for 30 days). Prolong lidocaine infusion and cardioversion were life saving.

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Anti-Arrhythmia AgentsAntimony Sodium GluconateAntiprotozoal AgentsChildElectric CountershockFemaleHumansLeishmaniasis, VisceralLidocaineTachycardia, VentricularCase ReportsJournal Article

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Arun K Baranwal, Ravi N Mandal, Rupa Singh, Sunit C Singhi. 2005. Sodium stibogluconate and polymorphic ventricular tachycardia.. https://pubmed.ncbi.nlm.nih.gov/15812130/

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