Centromeric chromatin makes its mark.

Elaine Dunleavy; Alison Pidoux; Robin Allshire

doi:10.1016/j.tibs.2005.02.007

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Centromeric chromatin makes its mark.

Elaine Dunleavy·Alison Pidoux·Robin Allshire

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Abstract

Post-translational modifications of core histones, particularly in the N terminus, seem to define different chromatin states in the genome. For instance, actively transcribed regions of euchromatin have a completely different set of 'marks' compared with silent heterochromatin. Recent analyses surprisingly demonstrate that, in addition to containing the histone H3 variant CENP-A, the centromeric chromatin that underlies the kinetochore bears a distinct combination of histone H3 modifications.

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Amino Acid Sequence Centromere Chromatin Histones Molecular Sequence Data Protein Processing, Post-Translational Journal Article Research Support, Non-U.S. Gov't Review

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Elaine Dunleavy, Alison Pidoux, Robin Allshire. 2005. Centromeric chromatin makes its mark.. https://doi.org/10.1016/j.tibs.2005.02.007

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