[Fluorescence studies on amoxicillin].

L Ma; L Chen; S Huang

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PubMed · 15819018

[Fluorescence studies on amoxicillin].

L Ma·L Chen·S Huang

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Abstract

The effects of pH, various organic solvents such as acetone, methanol, ethanol, surface-active agent on amoxicillin have been studied in detail. Put in pH=8 buffer solution, amoxicillin has strong fluorescence emission, excitaion wavelength of 277 nm, and emission wavelength of 303 nm. Calibration curve of amoxicillin was linear between 2 x 10(-5) and 2 x 10(-4) mol/L, with a regression coefficient of 0.9996. CTAB can enhance its fluorescence intensity. The results of fluorescence spectra of amoxicillin added with metal ions (Mg2+, Ca2+, Al3+, Ga3+) at pH=12 showed that there are interactions between amoxicillin and metal ions.

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Amoxicillin Anti-Bacterial Agents Drug Stability Spectrometry, Fluorescence Evaluation Study Journal Article Research Support, Non-U.S. Gov't

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L Ma, L Chen, S Huang. 1999. [Fluorescence studies on amoxicillin].. https://pubmed.ncbi.nlm.nih.gov/15819018/

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