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PubMed · 15833048

Molecular diagnostics by microelectronic microchips.

Maurizio Ferrari·Laura Cremonesi·Pierangelo Bonini·Stefania Stenirri·Barbara Foglieni
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Abstract

Molecular diagnostics is being revolutionized by the development of highly advanced technologies for DNA and RNA testing. One of the most important challenges is the integration of microelectronics to microchip-based nucleic acid technologies. The specific characteristics of these microsystems make the miniaturization and automation of any step of a molecular diagnostic procedure possible. This review describes the application of microelectronics to all the processes involved in a genetic test, particularly to sample preparation, DNA amplification and sequence variation detection.

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AnimalsBiosensing TechniquesDNAElectrochemistryHumansMicrochip Analytical ProceduresMolecular Diagnostic TechniquesPolymerase Chain ReactionRNAJournal ArticleReview

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Maurizio Ferrari, Laura Cremonesi, Pierangelo Bonini, Stefania Stenirri, Barbara Foglieni. 2005. Molecular diagnostics by microelectronic microchips.. https://doi.org/10.1586/14737159.5.2.183

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