Artificial liver support systems.

J George

Home/Archive/PubMed

PubMed · 15839451

Artificial liver support systems.

J George

View original source ↗Export metadata ↓

Abstract

Though artificial support systems for kidney failure have been widely available for the past several decades, it is only recently that they have become a promising treatment modality for liver failure. The various liver support systems include conventional dialysis, charcoal hemoperfusion, high volume plasma exchange, liver dialysis using sorbent technology, molecular readsorption recirculating system using albumin as the dialysate, bioartificial livers, extracorporeal liver assist device and extracorporeal organ perfusion. They are mainly used as a bridge to liver transplantation and occasionally in acute liver failure till the liver regenerates. The various methods of extracorporeal liver support that are available at present are assessed and those that appear to be promising are described.

Explore related subjects

Dialysis Extracorporeal Circulation Hemofiltration Hemoperfusion Humans Liver Liver Failure, Acute Liver Transplantation Liver, Artificial Peritoneal Dialysis Renal Dialysis Journal Article Review

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

J George. 2004. Artificial liver support systems.. https://pubmed.ncbi.nlm.nih.gov/15839451/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

Electrodialysis with bipolar membranes for sustainable development.

Electrodialysis with bipolar membranes (EDBM) is a kind of technology that integrates solvent and salt dissociation. It can realize salt conversion without second salt pollution or provide H+ and OH-/alkoxide ions in situ without salt introduction. Thus, it inherently possesses economical and environmental benefits. Moreover, its technological compatibility gives rise to new functions when it couples with other technologies, such as complexion, ion exchange, extraction, and adsorption. In view of the above peculiarities, EDBM has found many interesting applications in chemistry, food processing, biochemical industries, and environmental protection. However, its development has been restricted by such factors as lack of recognition of its contribution to industrial ecology, high membrane cost, insufficient research investment, and scarce operation experience. This paper compiles an introduction to this technology from the perspective of industrial ecology and conducts an extensive examination into EDBM applications. Its purpose is to gather synergic strength from academia, industry, and government to perfect EDBM for sustainable development.

Dialysis↗

PubMed2006

Comparative study on the regeneration of flue-gas desulfurizing agents by using conventional electrodialysis (ED) and bipolar membrane electrodialysis (BMED).

Piperazine is an ideal desulfurizing agent but the heat-stable salts formed in desulfurization have caused secondary pollution and waste of resources. In the previous paper, a method was reported to regenerate piperazine by using BMED. To find the variety of that regeneration process, we performed experiments on the regeneration of piperazine by using ED. In comparison, ED has higher piperazine yield and current efficiency, and much lower voltage drop and energy consumption. However, its process cost is higher than that of BMED due to an extra expenditure for the base and its tank and pumps. The process cost is estimated to be 0.96 dollar/kg Pz for BMED and 1.14 dollar/kg Pz for ED. Notably, BMED has more environmental benefits and will be more economically attractive as the control on secondary pollution is strengthened and the bipolar membrane cost decreases.

Dialysis↗

PubMed2006

Removal of fluoride from water using anion-exchange membrane under Donnan dialysis condition.

The transport of fluoride through Neosepta-ACM anion-exchange membrane has been studied as a function of feed phase and receiver phase concentration and co-existence anions under Donnan dialysis condition. It was observed that the transport of fluoride was maximum at pH 6 of feed phase and at pH 1 of receiver phase. Moreover, transport of fluoride increased with increase of feed and receiver phase concentration and decreased in the presence of other co-existence anions in the feed phase. The transport of fluoride was also correlated with the flux data and explained according to structure of membrane.

Dialysis↗