Efficient batch and continuous flow Suzuki cross-coupling reactions under mild conditions, catalysed by polyurea-encapsulated palladium (II) acetate and tetra-n-butylammonium salts.

Connie K Y Lee; Andrew B Holmes; Steven V Ley; Ian F McConvey; Bushra Al-Duri; Gary A Leeke; Regina C D Santos; Jonathan P K Seville

doi:10.1039/b418669a

PubMed · 15846438

Efficient batch and continuous flow Suzuki cross-coupling reactions under mild conditions, catalysed by polyurea-encapsulated palladium (II) acetate and tetra-n-butylammonium salts.

Connie K Y Lee·Andrew B Holmes·Steven V Ley·Ian F McConvey·Bushra Al-Duri·Gary A Leeke·Regina C D Santos·Jonathan P K Seville

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Abstract

Suzuki cross-coupling reactions are effected in both conventional organic solvents, under continuous flow conditions at 70 degree C, and in batch mode in supercritical carbon dioxide (scCO2), at temperatures as low as 40 degrees C in the presence of palladium(II) acetate microencapsulated in polyurea [PdEnCat] and tetra-n-butylammonium salts.

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Acetates Biphenyl Compounds Carbon Dioxide Catalysis Molecular Structure Organometallic Compounds Polymers Quaternary Ammonium Compounds Salts Temperature Journal Article Research Support, Non-U.S. Gov't

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Connie K Y Lee, Andrew B Holmes, Steven V Ley, Ian F McConvey, Bushra Al-Duri, Gary A Leeke, Regina C D Santos, Jonathan P K Seville. 2005-03-09. Efficient batch and continuous flow Suzuki cross-coupling reactions under mild conditions, catalysed by polyurea-encapsulated palladium (II) acetate and tetra-n-butylammonium salts.. https://doi.org/10.1039/b418669a

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