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A reliable coding system to define screening prostate-specific antigen tests was developed in a case-control study.

Peter S Bunting·Jan Neuman·Vivek Goel·Neil Fleshner·Jacek Kopec·Peter Levers·Padraig Warde
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Abstract

OBJECTIVE: To establish the reliability of a coding system for screening and diagnostic prostate-specific antigen (PSA) testing from patient charts. STUDY DESIGN AND SETTING: Two investigators reviewed 448 chart abstractions from a population-based case-control study of PSA screening in the Toronto area. The tests evaluated for reliability were transrectal ultrasound (TRUS), digital rectal examination (DRE), and prostate-specific antigen (PSA). RESULTS: DRE results were found in 87%, PSA results in 65%, and TRUS results in 12% of the 749 charts. Interobserver agreement was 94% for DRE texture (kappa =.885), 95% for DRE asymmetry (kappa = .868), 85% for DRE physician interpretation (kappa = .698), 97% for final DRE result (kappa = .856), and 87% for TRUS (kappa = .769). Physician interpretation modified the final result in only 6.2% of DREs. Interobserver agreement for PSA coding was 91% (kappa = .787). Of PSA results, pure PSA screening with no symptoms of obstructive urination was found in 19%, symptomatic PSA screening in 46%, and diagnostic PSA testing in 35%. CONCLUSION: We have developed a practical and reliable coding system for TRUS, DRE, and PSA in the context of a case-control study of PSA screening.

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Biomarkers, TumorCase-Control StudiesHumansMaleMass ScreeningMedical RecordsObserver VariationPalpationProstate-Specific AntigenProstatic NeoplasmsRectumUltrasonographyJournal ArticleMulticenter StudyResearch Support, Non-U.S. Gov't

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Peter S Bunting, Jan Neuman, Vivek Goel, Neil Fleshner, Jacek Kopec, Peter Levers, Padraig Warde. 2005. A reliable coding system to define screening prostate-specific antigen tests was developed in a case-control study.. https://doi.org/10.1016/j.jclinepi.2004.10.014

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