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CGHAnalyzer: a stand-alone software package for cancer genome analysis using array-based DNA copy number data.

Adam A Margolin·Joel Greshock·Tara L Naylor·Yael Mosse·John M Maris·Graham Bignell·Alexander I Saeed·John Quackenbush·Barbara L Weber
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Abstract

SUMMARY: This synopsis provides an overview of array-based comparative genomic hybridization data display, abstraction and analysis using CGHAnalyzer, a software suite, designed specifically for this purpose. CGHAnalyzer can be used to simultaneously load copy number data from multiple platforms, query and describe large, heterogeneous datasets and export results. Additionally, CGHAnalyzer employs a host of algorithms for microarray analysis that include hierarchical clustering and class differentiation. AVAILABILITY: CGHAnalyzer, the accompanying manual, documentation and sample data are available for download at http://acgh.afcri.upenn.edu. This is a Java-based application built in the framework of the TIGR MeV that can run on Microsoft Windows, Macintosh OSX and a variety of Unix-based platforms. It requires the installation of the free Java Runtime Environment 1.4.1 (or more recent) (http://www.java.sun.com).

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AlgorithmsAnimalsChromosome MappingComputer GraphicsDNA Mutational AnalysisGene DosageHumansNeoplasmsOligonucleotide Array Sequence AnalysisSoftwareUser-Computer InterfaceEvaluation StudyJournal Article

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Adam A Margolin, Joel Greshock, Tara L Naylor, Yael Mosse, John M Maris, Graham Bignell, Alexander I Saeed, John Quackenbush, Barbara L Weber. 2005-05-19. CGHAnalyzer: a stand-alone software package for cancer genome analysis using array-based DNA copy number data.. https://doi.org/10.1093/bioinformatics%2Fbti500

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