Benzophenones from Hypericum carinatum.

Ana Paula M Bernardi; Alexandre B F Ferraz; Daniela V Albring; Sérgio A L Bordignon; Jan Schripsema; Raquel Bridi; Carlos Severo Dutra-Filho; Amélia T Henriques; Gilsane Lino von Poser

doi:10.1021/np040149e

PubMed · 15921431

Benzophenones from Hypericum carinatum.

Ana Paula M Bernardi·Alexandre B F Ferraz·Daniela V Albring·Sérgio A L Bordignon·Jan Schripsema·Raquel Bridi·Carlos Severo Dutra-Filho·Amélia T Henriques·Gilsane Lino von Poser

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Abstract

Two new benzophenones were isolated from the leaves of Hypericum carinatum. Their structures were established on the basis of 2D NMR spectroscopic analyses and mass spectrometry as cariphenone A (6-benzoyl-5,7-dihydroxy-2,2,8-trimethyl-2H-chromene) (1) and cariphenone B (8-benzoyl-5,7-dihydroxy-2,2,6-trimethyl-2H-chromene) (2). Five known compounds, the phloroglucinol derivative uliginosin B (3), 1-eicosanol, sitosterol, stigmasterol, and campesterol, were also characterized. Compounds 1-3 were evaluated for their total antioxidant capacity through a total radical-trapping parameter assay. Only compound 1 showed moderate antioxidant activity, exhibiting inhibition of chemiluminescence similar to that of quercetin at the same concentration.

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Antioxidants Benzophenones Brazil Dose-Response Relationship, Drug Hypericum Luminescent Measurements Molecular Structure Phloroglucinol Plant Leaves Plants, Medicinal Quercetin Journal Article Research Support, Non-U.S. Gov't

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Ana Paula M Bernardi, Alexandre B F Ferraz, Daniela V Albring, Sérgio A L Bordignon, Jan Schripsema, Raquel Bridi, Carlos Severo Dutra-Filho, Amélia T Henriques, Gilsane Lino von Poser. 2005. Benzophenones from Hypericum carinatum.. https://doi.org/10.1021/np040149e

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