From sensing cellular sterols to assembling sensory structures.

John P Incardona

doi:10.1016/j.devcel.2005.05.011

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From sensing cellular sterols to assembling sensory structures.

John P Incardona

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Abstract

The genome of the nematode C. elegans is peppered with novel genes belonging to a superfamily whose members function in cellular cholesterol homeostasis (Niemann-Pick C1) and Hedgehog signal transduction (Patched) and biogenesis (Dispatched). In this issue of Developmental Cell and an analysis of a pair of Patched- and Dispatched-related proteins in C. elegans extends the superfamily's repertoire to include the formation of tubular organs.

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Animals Caenorhabditis elegans Caenorhabditis elegans Proteins Cholesterol Homeostasis Patched Receptors Receptors, Cell Surface Sense Organs Signal Transduction Sterols Journal Article

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John P Incardona. 2005. From sensing cellular sterols to assembling sensory structures.. https://doi.org/10.1016/j.devcel.2005.05.011

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