Dendritic spine geometry: functional implication and regulation.

Yasunori Hayashi; Ania K Majewska

doi:10.1016/j.neuron.2005.05.006

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Dendritic spine geometry: functional implication and regulation.

Yasunori Hayashi·Ania K Majewska

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Abstract

Dendritic spines are tiny protrusions on dendritic shafts where most excitatory synapses are located. Recent advances in imaging technologies have given us great insight into the function of spines as biochemical compartments. Here we review recent evidence suggesting that the geometry of dendritic spines controls postsynaptic calcium signaling and is bidirectionally regulated during synaptic plasticity.

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Animals Calcium Dendritic Spines Models, Neurological Neuronal Plasticity Receptors, Glutamate Signal Transduction Journal Article Review

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Yasunori Hayashi, Ania K Majewska. 2005-05-19. Dendritic spine geometry: functional implication and regulation.. https://doi.org/10.1016/j.neuron.2005.05.006

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