PubMed · 15948517
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Bill Mrazek. 2005. The Universal Prep.. https://pubmed.ncbi.nlm.nih.gov/15948517/
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We propose a new class of aperture-coded spectrometer that is optimized for the spectral characterization of diffuse sources. The instrument achieves high throughput and high spectral resolution by replacing the slit of conventional dispersive spectrometers with a more complicated spatial filter. We develop a general mathematical framework for deriving the required aperture codes and discuss several appealing code families. Experimental results validate the performance of the instrument.
A surface plasmon resonance (SPR) sensing technique based on polarization interferometry and angle modulation is presented. Its sensitivity is not a direct function of variation of reflection intensity, nor of phase shift. Rather, it is a function of the complex reflection coefficient. A three times standard deviation detection limit of 5.1 x 10(-7) refractive index units in a 2 Hz bandwidth is obtained with our experimental setup. A theoretical analysis shows that this technique can provide a wide linear measurement range. Moreover, the sensitivity is insensitive to the thickness of gold films over approximately 5 nm. This SPR sensing technique is suitable for physical, chemical, and biological research.