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PubMed · 15951098

Translational control during mitosis.

Magali Le Breton·Patrick Cormier·Robert Bellé·Odile Mulner-Lorillon·Julia Morales
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Abstract

Translation is now recognized as an important process in the regulation of gene expression. During the cell cycle, translation is tightly regulated. Protein synthesis is necessary for entry into and progression through mitosis and conversely, modifications of translational activity are observed during the cell cycle. This review focuses on translational control during mitosis (or M-phase) and the role of CDK1/cyclin B, the universal cell cycle regulator implicated in the G2/M transition, in protein synthesis regulation.

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CDC2 Protein KinaseCell CycleCyclin BCyclin B1G2 PhaseGene Expression RegulationMitosisPhosphorylationPolyadenylationProtein BiosynthesisRNA, MessengerJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Magali Le Breton, Patrick Cormier, Robert Bellé, Odile Mulner-Lorillon, Julia Morales. Translational control during mitosis.. https://doi.org/10.1016/j.biochi.2005.04.014

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