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PubMed · 15957003

Scoring proteomes with proteotypic peptide probes.

Bernhard Kuster·Markus Schirle·Parag Mallick·Ruedi Aebersold
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Abstract

Technologies for genome-wide analyses typically undergo a transition from a discovery phase to a scoring phase. In the discovery phase, the genomic universe is explored and all pertinent data are noted. In the scoring phase, relevant entities are screened to reveal groups of genes that are associated with specific biological processes or conditions. In this article, we propose that the transition from a discovery to a scoring phase is also essential, feasible and imminent for proteomics.

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Amino Acid SequenceAnimalsGenomeGenomicsHumansModels, GeneticMolecular Sequence DataPeptidesProtein KinasesProteinsProteomeJournal ArticleReview

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Bernhard Kuster, Markus Schirle, Parag Mallick, Ruedi Aebersold. 2005. Scoring proteomes with proteotypic peptide probes.. https://doi.org/10.1038/nrm1683

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