Tissue-engineering approaches for axonal guidance.

Ning Zhang; Honghai Yan; Xuejun Wen

doi:10.1016/j.brainresrev.2004.11.002

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Tissue-engineering approaches for axonal guidance.

Ning Zhang·Honghai Yan·Xuejun Wen

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Abstract

Owing to the profound impact of nervous system damage, extensive studies have been carried out aimed at facilitating axonal regeneration following injury. Tissue engineering, as an emerging and rapidly growing field, has received extensive attention for nervous system axonal guidance. Numerous engineered substrates containing oriented extracellular matrix molecules, cells or channels have displayed potential of supporting axonal regeneration and functional recovery. Most attempts are focused on seeking new biomaterials, new cell sources, as well as novel designs of tissue-engineered neuronal bridging devices, to generate safer and more efficacious neuronal tissue repairs.

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Animals Axons Humans Nerve Regeneration Spinal Cord Injuries Tissue Engineering Journal Article Review

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Ning Zhang, Honghai Yan, Xuejun Wen. 2005-01-13. Tissue-engineering approaches for axonal guidance.. https://doi.org/10.1016/j.brainresrev.2004.11.002

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