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PubMed · 15980437

AS2TS system for protein structure modeling and analysis.

A Zemla·C Ecale Zhou·T Slezak·T Kuczmarski·D Rama·C Torres·D Sawicka·D Barsky
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Abstract

We present a set of programs and a website designed to facilitate protein structure comparison and protein structure modeling efforts. Our protein structure analysis and comparison services use the LGA (local-global alignment) program to search for regions of local similarity and to evaluate the level of structural similarity between compared protein structures. To facilitate the homology-based protein structure modeling process, our AL2TS service translates given sequence-structure alignment data into the standard Protein Data Bank (PDB) atom records (coordinates). For a given sequence of amino acids, the AS2TS (amino acid sequence to tertiary structure) system calculates (e.g. using PSI-BLAST PDB analysis) a list of the closest proteins from the PDB, and then a set of draft 3D models is automatically created. Web services are available at http://as2ts.llnl.gov/.

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Capsid ProteinsDatabases, ProteinInternetModels, MolecularProtein ConformationSequence Analysis, ProteinSoftwareStructural Homology, ProteinJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.

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A Zemla, C Ecale Zhou, T Slezak, T Kuczmarski, D Rama, C Torres, D Sawicka, D Barsky. 2005-07-01. AS2TS system for protein structure modeling and analysis.. https://doi.org/10.1093/nar%2Fgki457

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