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PubMed · 15991339

PRISM: protein interactions by structural matching.

Utkan Ogmen·Ozlem Keskin·A Selim Aytuna·Ruth Nussinov·Attila Gursoy
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Abstract

Prism (http://gordion.hpc.eng.ku.edu.tr/prism) is a website for protein interface analysis and prediction of putative protein-protein interactions. It is composed of a database holding protein interface structures derived from the Protein Data Bank (PDB). The server also includes summary information about related proteins and an interactive protein interface viewer. A list of putative protein-protein interactions obtained by running our prediction algorithm can also be accessed. These results are applied to a set of protein structures obtained from the PDB at the time of algorithm execution (January 2004). Users can browse through the non-redundant dataset of representative interfaces on which the prediction algorithm depends, retrieve the list of similar structures to these interfaces or see the results of interaction predictions for a particular protein. Another service provided is interactive prediction. This is done by running the algorithm for user input structures.

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AlgorithmsInternetProtein ConformationProtein Interaction MappingSoftwareUser-Computer InterfaceJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.

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Utkan Ogmen, Ozlem Keskin, A Selim Aytuna, Ruth Nussinov, Attila Gursoy. 2005-07-01. PRISM: protein interactions by structural matching.. https://doi.org/10.1093/nar%2Fgki585

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