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PubMed · 16005278

Cellular signalling: STIMulating calcium entry.

Jonathan S Marchant
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Abstract

The molecular identity of the signal coupling intracellular Ca(2+) store depletion to the activation of Ca(2+) entry has long resisted exposure. Two recent studies independently implicate the STIM protein family as essential components in this coupling. These data provide new impetus to resolve how store Ca(2+) content is sensed and communicated to store-operated Ca(2+) channels at the cell surface.

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Biological Transport, ActiveCalciumCalcium ChannelsEndoplasmic ReticulumHeLa CellsHumansIon TransportMembrane ProteinsModels, BiologicalNeoplasm ProteinsRNA InterferenceSignal TransductionStromal Interaction Molecule 1Journal ArticleReview

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Jonathan S Marchant. 2005-07-12. Cellular signalling: STIMulating calcium entry.. https://doi.org/10.1016/j.cub.2005.06.035

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