Dynamic range relations for auditory primary afferents.

Lance Nizami

doi:10.1016/j.heares.2005.05.002

Home/Archive/PubMed

PubMed · 16005586

Dynamic range relations for auditory primary afferents.

Lance Nizami

View original source ↗Export metadata ↓

Abstract

Dynamic range is one of four attributes typically assigned to the plot of firing rate vs. stimulus level of an auditory primary afferent. Dynamic range is generally understood to be the contiguous range of sound-pressure-level over which the neuron can indicate some small level change. Typically, however, dynamic range has been quantified as the width in decibels between the endpoints of the rate-level plot, which is not a measure of sensitivity to level change. A sensitivity measure is provided here by first deriving an equation for the intensity-difference limen (DL) in terms of attributes of the rate-level curve. The result is a generally U-shaped curve of DL vs. level. Any given criterion DL corresponds to a horizontal line cutting the DL curve at two points, with the separation in decibels between those points providing a dynamic range for that DL criterion. Plotting the dynamic ranges vs. the respective DLs yields a dynamic range curve. These were made for 62 afferents from the cat. The dynamic ranges of sloping-saturating rate-level plots do not exceed those for sigmoidal plots until the DL criterion reaches 50 dB, supporting the conclusion of Palmer and Evans [Cochlear fibre rate-intensity functions: no evidence for basilar membrane nonlinearities, Hearing Research 2 (1980) 319-326] that sloping saturation is not a reflection of cochlear nonlinearity.

Explore related subjects

Acoustic Stimulation Animals Auditory Cortex Auditory Pathways Auditory Perception Cats Discrimination, Psychological Evoked Potentials, Auditory Hearing Models, Neurological Journal Article

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

Lance Nizami. 2005-07-07. Dynamic range relations for auditory primary afferents.. https://doi.org/10.1016/j.heares.2005.05.002

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2008

Sensory filtering phenomenology in PTSD.

Disrupted sensory filtering, or problems with suppressing irrelevant environmental sensory stimuli, has been reported in individuals with posttraumatic stress disorder (PTSD). However, the relationship of sensory filtering deficits to specific PTSD symptoms versus an association with general trauma exposure is unclear. These relationships were examined by administering self-report measures of trauma exposure, PTSD, and sensory gating phenomenology to undergraduate participants with PTSD (n=32), with trauma history but without PTSD (n=144), and with minimal trauma history (n=153). Subjects with PTSD reported greater filtering disruption than individuals in the trauma only and low trauma groups, who did not differ. Individuals endorsing reexperiencing and numbing symptoms, and females endorsing hypervigilance, reported disrupted sensory filtering phenomenology. These results suggest that impaired filtering differentiates between individuals with PTSD symptoms and asymptomatic individuals exposed to multiple traumas and low-trauma controls.

Acoustic Stimulation↗

PubMed2007

Hypoglycemia reduces the blood-oxygenation level dependent signal in primary auditory and visual cortex: a functional magnetic resonance imaging study.

Studies of the effects of hypoglycemia on the brain using neurocognitive testing have suggested that mainly complex functions subserved by secondary and tertiary cortex are affected by mild to moderate hypoglycemia and that intensively treated patients with Type I diabetes mellitus (T1DM) may have altered sensitivity to the central nervous system effects of hypoglycemia. Functional magnetic resonance imaging provides a sensitive, regionally-specific probe of possible neurophysiologic changes related to hypoglycemia in the brain. Eleven intensively-treated T1DM patients and 11 matched non-diabetic controls took part in a 2-day protocol in which functional magnetic resonance imaging (MRI) was used to measure changes in the patterns of brain activation produced by simple auditory and visual stimuli in different conditions. On one day, participants were euglycemic the entire time. On the other day, an initial 50-min euglycemic period was followed by a 50-min hypoglycemic period. Results indicated that hypoglycemia reduced the amplitude of the blood-oxygenation level dependent response in primary auditory and visual cortex to simple auditory and visual stimuli. The latency and duration of the transient hemodynamic response function were not affected. Responses to hypoglycemia were similar in diabetic and non-diabetic participants. These results suggest that mild to moderate hypoglycemia may alter the balance of blood flow and oxygen extraction when glucose levels are lowered. Intensively-treated T1DM, with its attendant frequent hypoglycemic episodes, did not seem to alter hypoglycemic responses in primary visual and auditory cortex.

Acoustic Stimulation↗

PubMed2007

Song discrimination learning in zebra finches induces highly divergent responses to novel songs.

Perceptual biases can shape the evolution of signal form. Understanding the origin and direction of such biases is therefore crucial for understanding signal evolution. Many animals learn about species-specific signals. Discrimination learning using simple stimuli varying in one dimension (e.g. amplitude, wavelength) can result in perceptual biases with preferences for specific novel stimuli, depending on the stimulus dimensions. We examine how this translates to discrimination learning involving complex communication signals; birdsongs. Zebra finches (Taeniopygia guttata) were trained to discriminate between two artificial songs, using a Go/No-Go procedure. The training songs in experiment 1 differed in the number of repeats of a particular element. The songs in experiment 2 differed in the position of an odd element in a series of repeated elements. We examined generalization patterns by presenting novel songs with more or fewer repeated elements (experiment 1), or with the odd element earlier or later in the repeated element sequence (experiment 2). Control birds were trained with only one song. The generalization curves obtained from (i) control birds, (ii) experimental birds in experiment 1, and (iii) experimental birds in experiment 2 showed large and systematic differences from each other. Birds in experiment 1, but not 2, responded more strongly to specific novel songs than to training songs, showing 'peak shift'. The outcome indicates that learning about communication signals may give rise to perceptual biases that may drive signal evolution.

Acoustic Stimulation↗