How well are protein structures annotated in secondary databases?

Kristian Rother; Elke Michalsky; Ulf Leser

doi:10.1002/prot.20520

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How well are protein structures annotated in secondary databases?

Kristian Rother·Elke Michalsky·Ulf Leser

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Abstract

We investigated to what extent Protein Data Bank (PDB) entries are annotated with second-party information based on existing cross-references between PDB and 15 other databases. We report 2 interesting findings. First, there is a clear "annotation gap" for structures less than 7 years old for secondary databases that are manually curated. Second, the examined databases overlap with each other quite well, dividing the PDB into 2 well-annotated thirds and one poorly annotated third. Both observations should be taken into account in any study depending on the selection of protein structures by their annotation.

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Amino Acid Sequence Databases, Protein Protein Conformation Proteins Publishing Journal Article Research Support, Non-U.S. Gov't

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Kristian Rother, Elke Michalsky, Ulf Leser. 2005-09-01. How well are protein structures annotated in secondary databases?. https://doi.org/10.1002/prot.20520

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