Getting a molecular grasp on Hox contextual activity.

Samir Merabet; Jacques Pradel; Yacine Graba

doi:10.1016/j.tig.2005.07.001

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Getting a molecular grasp on Hox contextual activity.

Samir Merabet·Jacques Pradel·Yacine Graba

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Abstract

Hox genes encode evolutionarily conserved transcription factors with key functions in development and evolution. Although the multitude of processes individually controlled by Hox proteins highlights the importance of contextual information in setting their diverse activities, the underlying molecular mechanisms still remain elusive. A recent study identified novel Hox molecular partners, whose properties set a conceptual framework to understand how Hox proteins use and integrate contextual information.

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Animals Body Patterning Drosophila Drosophila Proteins Gene Expression Regulation, Developmental Genes, Homeobox Homeodomain Proteins Protein Binding Transcription Factors Journal Article Review

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Samir Merabet, Jacques Pradel, Yacine Graba. 2005. Getting a molecular grasp on Hox contextual activity.. https://doi.org/10.1016/j.tig.2005.07.001

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