Early and late B-cell development in the mouse.

K Rajewsky

doi:10.1016/0952-7915(92)90008-3

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Early and late B-cell development in the mouse.

K Rajewsky

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Abstract

A common principle in B-cell development is the stringent selection of cells expressing appropriate antibody V regions as surface receptors. Cells failing to do so appear destined to rapid death. These life-death decisions are mediated by signals whose nature is not yet understood but whose generation involves immunoglobulin receptor complexes on B cells and B-cell progenitors.

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Animals B-Lymphocytes Cell Death Cell Differentiation Mice Receptors, Antigen, B-Cell Journal Article Review

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K Rajewsky. 1992. Early and late B-cell development in the mouse.. https://doi.org/10.1016/0952-7915(92)90008-3

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