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Building integrated approaches for the proteomics of complex, dynamic systems: NIH programs in technology and infrastructure development.

Douglas M Sheeley·Joseph J Breen·Susan E Old
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Abstract

Proteomics technology and methods remain inadequate. Technological constraints contribute to an artificially static view of complex biological systems and a barrier between quantitative and interaction studies. Several NIH programs combine proteomics technology development with research on challenging biological problems to drive progress. A new initiative of the NIH Roadmap focuses on characterization of dynamic systems. The success of these programs will be judged by their impact on relevant biological problems.

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Biomedical ResearchHumansNational Institutes of Health (U.S.)ProteomicsTechnologyUnited StatesJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.

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Douglas M Sheeley, Joseph J Breen, Susan E Old. Building integrated approaches for the proteomics of complex, dynamic systems: NIH programs in technology and infrastructure development.. https://doi.org/10.1021/pr050066z

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