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Cell migration in 3D matrix.

Sharona Even-Ram·Kenneth M Yamada
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Abstract

The ability of cells to migrate within the extracellular matrix and to remodel it depends as much on the physical and biochemical characteristics of a particular matrix as on cellular properties. Analyzing the different modes of migration of cells in matrices, and how cells switch between these modes, is vital for understanding a variety of physiological and pathological processes. Recent work provides new insights, but also raises some debates about the mechanisms and regulation of cell migration in three-dimensional matrices.

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AnimalsBasement MembraneCell MovementExtracellular MatrixHumansModels, BiologicalMonomeric GTP-Binding ProteinsSignal TransductionJournal ArticleReview

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Sharona Even-Ram, Kenneth M Yamada. 2005. Cell migration in 3D matrix.. https://doi.org/10.1016/j.ceb.2005.08.015

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