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PubMed · 16120084

Maternal atopy and changes in parity.

J Sunyer·J M Antó·E Plana·C Janson·D Jarvis·S Kony·E R Omenaas·C Svanes·M Wjst·B Leynaert·European Community Respiratory Health Study
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Abstract

BACKGROUND: Atopic women tend to have fewer children, although atopy may favour conception. OBJECTIVE: To assess whether atopy is associated with the number of new births and whether changes in parity are associated with a change in atopy in a cohort of young women. METHODS: Women had atopy (defined as the presence of serum-specific IgE against common aeroallergens) measured in the European Community Respiratory Health Study during the years 1991--92 (n=4580). About 9 years later, 2844 (62.1%) were recontacted and 2414 (52.7%) had atopy measured again. RESULTS: Atopic women had fewer children at baseline than non-atopic women but the association disappeared at the end of the follow-up. Atopy tended to increase parity during the follow-up, but in a non-statistically significant way (relative risk=1.08; 0.86-1.35, after adjusting for number of children at baseline, age, length of follow-up, education or social class). Prevalence of atopy during the follow-up changed by the same magnitude whatever the birth cohort and the change in the number of children (P for interaction >0.7). CONCLUSION: Atopic women did not have a significantly higher fertility rate but they may postpone having their first child compared with non-atopic women. We are unable to confirm the hypothesis that atopy in women may decrease with successive pregnancies.

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AdultAllergensFemaleFollow-Up StudiesHumansHypersensitivityImmune ToleranceImmunoglobulin EMaternal AgeMothersParityPregnancyPrevalenceRisk FactorsSocioeconomic FactorsJournal ArticleMulticenter StudyResearch Support, Non-U.S. Gov't

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J Sunyer, J M Antó, E Plana, C Janson, D Jarvis, S Kony, E R Omenaas, C Svanes, M Wjst, B Leynaert, European Community Respiratory Health Study. 2005. Maternal atopy and changes in parity.. https://doi.org/10.1111/j.1365-2222.2005.02300.x

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