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Singing-driven gene expression in the developing songbird brain.

Frank Johnson·Osceola Whitney
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Abstract

Neural and behavioral development arises from an integration of genetic and environmental influences, yet specifying the nature of this interaction remains a primary problem in neuroscience. Here, we review molecular and behavioral studies that focus on the role of singing-driven gene expression during neural and vocal development in the male zebra finch (Taeniopygia guttata), a songbird that learns a species-typical vocal pattern during juvenile development by imitating an adult male tutor. A primary aim of our lab has been to identify naturally-occurring environmental influences that shape the propensity to sing. This ethological approach underlies our theoretical perspective, which is to integrate the significance of singing-driven gene expression into a broader ecological context.

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Age FactorsAnimalsBrainGene Expression Regulation, DevelopmentalImmediate-Early ProteinsLearningSex FactorsSongbirdsVocalization, AnimalJournal ArticleReview

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Frank Johnson, Osceola Whitney. 2005-08-29. Singing-driven gene expression in the developing songbird brain.. https://doi.org/10.1016/j.physbeh.2005.08.009

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