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PubMed · 16141064

Fewer genes, more noncoding RNA.

Jean-Michel Claverie
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Abstract

Recent studies showing that most "messenger" RNAs do not encode proteins finally explain the long-standing discrepancy between the small number of protein-coding genes found in vertebrate genomes and the much larger and ever-increasing number of polyadenylated transcripts identified by tag-sampling or microarray-based methods. Exploring the role and diversity of these numerous noncoding RNAs now constitutes a main challenge in transcription research.

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AnimalsGenesGenome, HumanGenomicsHumansMiceProteinsRNA, UntranslatedTranscription, GeneticJournal ArticleResearch Support, Non-U.S. Gov't

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Jean-Michel Claverie. 2005-09-02. Fewer genes, more noncoding RNA.. https://doi.org/10.1126/science.1116800

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