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Preventing relapse/recurrence in recurrent depression with cognitive therapy: a randomized controlled trial.

Claudi L H Bockting·Aart H Schene·Philip Spinhoven·Maarten W J Koeter·Luuk F Wouters·Jochanan Huyser·Jan H Kamphuis
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Abstract

This article reports on the outcome of a randomized controlled trial of cognitive group therapy (CT) to prevent relapse/recurrence in a group of high-risk patients diagnosed with recurrent depression. Recurrently depressed patients (N = 187) currently in remission following various types of treatment were randomized to treatment as usual, including continuation of pharmacotherapy, or to treatment as usual augmented with brief CT. Relapse/recurrence to major depression was assessed over 2 years. Augmenting treatment as usual with CT resulted in a significant protective effect, which intensified with the number of previous depressive episodes experienced. For patients with 5 or more previous episodes (41% of the sample), CT reduced relapse/recurrence from 72% to 46%. Our findings extend the accumulating evidence that cognitive interventions following remission can be useful in preventing relapse/recurrence in patients with recurrent depression.

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Cognitive Behavioral TherapyMajor Depressive DisorderFemaleHumansMaleMiddle AgedSecondary PreventionJournal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov't

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Claudi L H Bockting, Aart H Schene, Philip Spinhoven, Maarten W J Koeter, Luuk F Wouters, Jochanan Huyser, Jan H Kamphuis. 2005. Preventing relapse/recurrence in recurrent depression with cognitive therapy: a randomized controlled trial.. https://doi.org/10.1037/0022-006x.73.4.647

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