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Iron overload and chelation.

Chaim Hershko·Gabriela Link·Abraham M Konijn·Z Ioav Cabantchik
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Abstract

Iron is one of the most common elements in nature. As a transition metal it is very efficient in electron transport and redox reactions. The proteins and enzymes in which iron is an essential component play a key role in respiration, energy production, detoxification of harmful oxygen species and cell replication. Despite the abundance of iron in nature, the solubility of its stable ferric form is extremely low. Hence, living organisms were compelled to develop efficient mechanisms for iron transport and storage.

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Chelation TherapyHumansIron Chelating AgentsIron OverloadSiderophoresTreatment OutcomeJournal ArticleReview

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Chaim Hershko, Gabriela Link, Abraham M Konijn, Z Ioav Cabantchik. 2005. Iron overload and chelation.. https://doi.org/10.1080/10245330512331390294

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