MAP kinases in immune responses.

Yong Liang Zhang; Chen Dong

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PubMed · 16212907

MAP kinases in immune responses.

Yong Liang Zhang·Chen Dong

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Abstract

MAP kinases are evolutionarily conserved signaling regulators from budding yeast to mammals and play essential roles in both innate and adaptive immune responses. There are three main families of MAPKs in mammals. Each of them has its own activators, inactivators, substrates and scaffolds, which altogether form a fine signaling network in response to different extracellular or intracellular stimulation. In this review, we summarize recent advances in understanding of the regulation of MAP kinases and the roles of MAP kinases in innate and adaptive immune responses.

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Animals Enzyme Activation Humans Immunity, Innate Lymphocyte Activation Mitogen-Activated Protein Kinases Signal Transduction T-Lymphocytes Journal Article Review

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Yong Liang Zhang, Chen Dong. 2005. MAP kinases in immune responses.. https://pubmed.ncbi.nlm.nih.gov/16212907/

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