Cell cycle: how cyclin E got its groove back.

Markus Welcker; Bruce Clurman

doi:10.1016/j.cub.2005.09.018

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Cell cycle: how cyclin E got its groove back.

Markus Welcker·Bruce Clurman

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Abstract

CDK1 has long been known to orchestrate the passage of mammalian cells into and through mitosis. Recent work revisits the idea that CDK1, in conjunction with cyclin E, participates in S-phase entry as well. The new results shed light on a recent cell-cycle mystery, and provide another dramatic example of apparent functional redundancy among cyclins and cyclin-dependent kinases.

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Animals CDC2 Protein Kinase Cyclin E Cyclin-Dependent Kinase 2 Mice Models, Biological S Phase Yeasts Journal Article Review

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Markus Welcker, Bruce Clurman. 2005-10-11. Cell cycle: how cyclin E got its groove back.. https://doi.org/10.1016/j.cub.2005.09.018

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